Lin28b regulates age-dependent differences in murine platelet function
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چکیده
منابع مشابه
Connexin40 regulates platelet function
The presence of multiple connexins was recently demonstrated in platelets, with notable expression of Cx37. Studies with Cx37-deficient mice and connexin inhibitors established roles for hemichannels and gap junctions in platelet function. It was uncertain, however, whether Cx37 functions alone or in collaboration with other family members through heteromeric interactions in regulation of plate...
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Platelets play a vital role in maintaining haemostasis. Human platelet activation depends on Ca2+ release, leading to cell activation, granule secretion and aggregation. NAADP (nicotinic acid-adenine dinucleotide phosphate) is a Ca2+-releasing second messenger that acts on acidic Ca2+ stores and is used by a number of mammalian systems. In human platelets, NAADP has been shown to release Ca2+ i...
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ژورنال
عنوان ژورنال: Blood Advances
سال: 2019
ISSN: 2473-9529,2473-9537
DOI: 10.1182/bloodadvances.2018020859